26. To prevent cells with damaged DNA from passing through the G, checkpoint, AT

Question

26. To prevent cells with damaged DNA from passing through the G, checkpoint, ATR or ATM Chk1 or Chk2, which then phosphorylate and a) phosphorylate; inhibit protein phosphatase Cdc25. phosphorylate; stimulate dephosphorylate; inhibit c. d. dephosphorylate; stimulate 27. Your answer to 26 has a specific affect on cdc25 (t modification and the fate of cdc25 affect co hat's obvious from the question). How does th mmitment to s (DNA replication)? Be specific! Do not just repeat what's written in #26!! (This is not about cdc45: it's about cdc25 function) ATM ATR are Kinases that Phosphory late hkychkz ous they Coh Cycle atrrest(atest) ATM: recomgunes dsDNA breake .ntio)

Explanation / Answer

27. The phosphorylation of M-Cdk which itself is a complex of Cdk1 and cyclin B is reponsible for the activation of cdc25. Cdc25 in turn activates cyclin dependent kinases by dephosphorylation of the active site of Cdk residues. Together with the help of cdk and enzyme namely cdc25A-C, it controls transition of the cell from G1 to S phase.

Related Questions

Navigate

• Browse (All)
• Browse 2
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.