20. The pro-B cell: is the site of light chain rearrangement b. a. proceeds to t
ID: 208655 • Letter: 2
Question
20. The pro-B cell: is the site of light chain rearrangement b. a. proceeds to the next step (pre-B cell) about 98% of the time c. is the site of heavy chain rearrangement d. is the site of heavy and light chains combining 21. During negative selection of immature B cells, there are 3 possible outcomes. Circle the 3 outcomes. a. B cell changes into T cell b. B cell activated to plasma cell c. B cell receptor is self-tolerant, development continues d. Inactivated B cell has successful receptor editing e. clonal deletion with apoptosis f. B cell turns into a B-1 cell 22. What is the first antibody produced during an immune response to antigen? e. IgM a. IgA b. IgD c. IgE d. IgG 23. To which cells does IgE not bind? a. mast cells b. epithelial c. eosinophils d. basophils 24. Germinal centers: a. b. c. d. e. are in the T-cell area of secondary lymphoid tissue are in the B-cell area of secondary lymphoid tissue contain rapidly dividing B and T cells cause " swollen glands" all are true except a.Explanation / Answer
20-d
21-d,e
22-e
23-b
24-b(Germinal centers or germinal centres (GC) are sites within secondary lymphoid organs where mature B lymphocytes proliferate, differentiate, and mutate their antibody genes)
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