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The Hardy-Weinberg equation can be used to calculate the genetic variation of a

ID: 208010 • Letter: T

Question

The Hardy-Weinberg equation can be used to calculate the genetic variation of a population in equilibrium (i.e., it is not evolving). Basically, Hardy-Weinberg equilibrium states that the amount of genetic variation is constant from one generation to the next – that is, the frequency of alleles remains the same over time.

The Hardy-Weinberg equation is very simple: p2 + 2pq + q2 = 1

Imagine we are following a single gene with two alleles, A and a. Based on the Hardy-Weinberg equation,

a) What is the frequency of the following genotypes:

AA: _____                  Aa: _____       aa: _____

b) What is the frequency of each allele:

A: _____                     a: _____

Explanation / Answer

According to Hardy Weinberg law if the equation is- p2 + 2pq + q2 then

The frequency of genotypes would be:

AA- p2

Aa - pq

And -aa - q2

And the frequency of each gene can be calculated by

A - p and a -q.

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