1 a. John has a hemoglobin of 6.0 g/dL and his physician has sent a type and scr

Question

1 a. John has a hemoglobin of 6.0 g/dL and his physician has sent a type and screen to the blood bank for processing and has also ordered 4 units of blood. Following processing John’s blood type in B positive with a positive antibody screen. Following antibody identification John has 2 antibodies, Anti-Jka and Anti-S. The antigens have the following frequency in the population: Jka+ = 77% and S+ = 55%. Determine how many units you would need to screen in the blood bank to find 4 antigen negative units for John.

1b. Do you think that the blood bank would be able to find 4 units negative for Jka and S in their inventory? Why or why not?   

Explanation / Answer

1. Percent of blood compatible with that antibody and if more than one antibody, multiply percentages together. If you are given the frequency of the antigen, subtract frequency from 100 to get the percent compatible.

Like john has following antigen frequency

JKa+ = 77% then 100-77 = 23 means 23/100= 0.23

S+ = 55% then 100-55 = 45 means 45/100= 0.45

then multiply these two percentage = 0.23* 0.45= 0.1035 % compatible

Number of units to be tested to find two units compatible = N

N= 4units

then 4/ 0.1035 = 38.64 round of 39

you would need 39 units to find 4 antigen negative units for John.

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