1. True or False: Toxicology has a strong early history of individuals who were
ID: 20733 • Letter: 1
Question
1. True or False: Toxicology has a strong early history of individuals who were infamous as poisoners (Points: 1)True
False
2. Toxicant injury always results in permanent changes. (Points: 1)
True
False
3. Cellular swelling is a sign of early injury. (Points: 1)
True
False
4. The best definition of a toxin is: (Points: 1)
any chemical that is foreign to the body
any substance that can potentially produce toxicity
any substance that if present in the body in relatively small amounts may produce damage
any poisonous substance produced by an organism
5. Which of the following is considered to be important in protecting individuals from chemicals? (Points: 1)
Type of chemicals they are exposed to
The potential levels of exposure
The toxicity of the chemicals
All of the above
6. The normal process of cell death is called: (Points: 1)
transcription
metabolic activation
apoptosis
transformation
7. A process of tissue destruction characterized by rapid structural and biochemical changes: (Points: 1)
Necrosis
Apoptosis
Promotion
Epigenesis
8. A common cellular target for chemical injury is: (Points: 1)
cell membrane
DNA
Protein
All of the above
9. Which term describes an active, orderly process for eliminating genetically damaged or dead cells without inflammatory reactions? (Points: 1)
Necrosis
Apoptosis
Mitosis
Fibrosis
10. Toxicity can be manifested by (Points: 1)
cytotoxicity
necrosis
lethal synthesis
all the above
11. NOAEL refers to: (Points: 1)
Lowest data point at which there was not an observed toxic or adverse effect
Highest data point at which there was not an observed toxic or adverse effect
Lowest data point at which there was an observed toxic or adverse effect
Highest data point at which there was an adverse toxic or adverse effect
12. LOAEL refers to: (Points: 1)
Lowest data point at which there was not an observed toxic or adverse effect
Highest data point at which there was not an observed toxic or adverse effect
Lowest data point at which there was an observed toxic or adverse effect
Highest data point at which there was an adverse toxic or adverse effect
13. Dose standardization is best done by (Points: 1)
weight
height
age
all of the above
14. The degree of penetration of a toxicant depends on (Points: 1)
Size/shape of toxicant.
Lipid solubility/hydrophobicity.
Charge/polarity.
All of the above
15. Which factor is important in determining net diffusion of a toxicant (Points: 1)
size of the molecule
degree of ionization
water solubility
all of above
Explanation / Answer
True False True
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