7 A) Which of the following statements is FALSE? Proteolytic cleavage of protein

ID: 206897 • Letter: 7

Question

7 A) Which of the following statements is FALSE?

Proteolytic cleavage of proteins can activate their activity.

Phosphorylation by kinases is an irreversible covalent modification that alters protein function.

Hemoglobin is a protein that exhibits cooperativity in binding its ligand, oxygen, thereby increasing its effectiveness.

The activity of GTPases is regulated by the association of GTP or GDP with the protein.

7 B) Which of the following techniques is the least useful to separate proteins based on their size?

differential centrifugation

gel filtration chromatography

two-dimensional gel electrophoresis

SDS-PAGE

7A) Phosphorylation by kinases is an irreversible covalent modification that alters protein function IS FALSE

Phosphorylation by kinases is an Reversible covalent modification that alters protein function

Reversible phosphorylation results in the conformational change in the structure of enzymes and receptors to become activated or deactivated

7B) 2D GEL Electrophoresis technique is the least useful to separate proteins based on their size

2D GEL Electrophoresis is mainly depended on the Isoelectric focussing which separates the proteins based on their isoelectric points (pI)

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