You have found that a mutation in a gene for a certain transcription factor resu

Question

You have found that a mutation in a gene for a certain transcription factor results in a defect in cartilage formation, but has no effect on heart formation. A possible explanation would be:

The gene is not expressed in the heart and therefore the mutation has no effect in that particular cell type.

The gene is expressed in the heart but the mutation prevents the protein from activating transcription in the heart.

There is no gene for that transcription factor in the heart and therefore the protein is not made in that cell type.

The gene is not expressed in the heart and therefore the mutation has no effect in that particular cell type.

The gene is expressed in the heart but the mutation prevents the protein from activating transcription in the heart.

There is no gene for that transcription factor in the heart and therefore the protein is not made in that cell type.

Explanation / Answer

The correct answer is option A that is gene is not expressed in the heart and therefore the mutation has no effect in that particular cell type because that is the only possible explanation why the mutation in gene did not affect the heart formation.

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