In a single cell type, Gene A requires the binding of TF1, TF2 and TF3 to its re

Question

In a single cell type, Gene A requires the binding of TF1, TF2 and TF3 to its regulatory region, while Gene B requires the binding of TF1, TF3 and TF4 to its regulatory region. How would a mutation in the gene for TF2 affect the expression of these two genes?

Both genes would be expressed

Gene A would be expressed, but Gene B would not

Gene B would be expressed, but Gene A would not

Neither gene would be expressed

Both genes would be expressed

Gene A would be expressed, but Gene B would not

Gene B would be expressed, but Gene A would not

Neither gene would be expressed

Explanation / Answer

A. Both genes would be expressed.

Because the both genes exist in a same cell and they played equal role to regulate the cell function. Both transcription factors induce a largely overlapping set of genes, including many of the host-induced genes on the accessory chromosome including the effector genes. This demonstrates the existence of extensive transcriptional connections between accessory and core chromosomes.

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