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Mutations that inhibit Rb gene expression will have what effect on cell prolifer

ID: 205954 • Letter: M

Question

Mutations that inhibit Rb gene expression will have what effect on cell proliferation?

E) There will be no effect on cell proliferation; only apoptosis occurs.

Thanks,

A) Cells will proliferate less because growth factors are absent. B) Cells will proliferate more because growth factors are produced in excess. C) Cells will proliferate more, regardless of growth factor concentration. D) Cells will proliferate less, even if excess growth factors are present.

E) There will be no effect on cell proliferation; only apoptosis occurs.

Thanks,

Explanation / Answer

The correct answer is option C that is cells will proliferate more, regardless of growth factor concentration because Rb gene is involved in tumor supression and when mutation occurs that inhibit the Rb gene then it will lead to cancer and cancerous cells do not require growth factors to proliferate, they proliferate regardless of growth factors are present or not.

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