1. Which of the following statements concerning DNA replication is FALSE? A. DNA
ID: 205873 • Letter: 1
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1. Which of the following statements concerning DNA replication is FALSE? A. DNA polymerase adds nucleotides to the growing strand. B. Okazaki fragments are due to the discontinuous synthesis of both strand C. DNA synthesis always proceeds in a 5' 3' direction. s. DNA synthesis is bidirectional DNA synthesis begins at the origin of replication 2. Enzymes called the DNA helix during replication. y. topoisomerases form breaks in the DNA molecules to prevent the formation of kinks in B. single-strand binding proteins C. DNA polymerases D. RNA polymerases E. DNA ligases 3. Which of the statements about the newly synthesized strand of a human chromosome is true? A. It was synthesized from a single origin solely by continuous DNA synthes It was synthesized from a single origin by a mixture of continuous and discontinuous DNA synthesis. C. It was synthesized from multiple origins solely by discontinuous DNA synthesis It was synthesized from multiple origins by mixture of continuous and discontinuous DNA synthesis. 4. Which of these enzymes for DNA replication is NOT appropriately identified? DNA ligase: joins Okazaki fragments together /B: DNA polyrnerase: proofreads DNA C. topoisomerase: form breaks in DNA to relieve supercoiling helicase: unwinds DNA E. not eerreet 5. When describing DNA replication, the following enzymes are necessary EXCEPT EDNA polymerase helicase topoisomerase D. DNA ligase E aminoacyl-tRNA synthetase All of these statements about telomeres are true EXCEPT telomeres are short, protein coding sequences of DNA B. telomeres could be involved in aging telomeres shorten slightly with each cell cycle telomeres can be replenished with telomerase telomeres are repetitive sequences cells and is the site where 7. a TATA box is seen in K. bacterial; RNA polymerase binds . eukaryotic; DNA ligase cleaves introns eukaryotie; RNA polymerase binds both bacterial and eukaryotic; transcription factors bind bacterial; a repressor protein binds 8. In order for transeription to occur, all of these are necessary EXCEPT A. DNA template B. NTPs (nucleoside triphosphates) RNA primer D. promoter sequences E. RNA polymerase to transcribe the majority of eukaryotic genes 9. Transcription uses e transcriptase B. RNA polymeraseI C. RNA polymerase II D. RNA polymerase III 10. Which of the following does not occur before a eucaryotic mRNA is exported from the nucleus? A. The ribosome binds to the mRNA B. The mRNA is polyadenylated at its 3' end 7-methyl-G is added in a 5' to 5' linkage to the mRNA. D. RNA polymerase dissociatesExplanation / Answer
Answer 1) statement B is false because okazaki fragments are formed only in 1 strand which is discontinuous known as lagging strand whereas leading stand shows continous synthesis. Answer 2) option A is correct. Topoisomerase in involves in preventing the overwinding of the dna helix by inducing negative supercoils. It thus helps in preventing the Dna from tangling . Answer 3) option D is correct. This is because eukaryotes have multiple origins as they are multirepliconic in nature and since they show semi- discontinous pattern of replication so both continous and dis-continous replication occurs. Answer 5) option E is correct as aminoacyl t-rna synthetase is involved in translation machinery of proteins. Answer 4 ) option E is correct as all the enzymes are necessary for replication with their roles specified already.
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