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History: M, a 48-year-old woman, presented to the physician with a long history

ID: 204939 • Letter: H

Question

History:
M, a 48-year-old woman, presented to the physician with a long history of dysfunctional uterine bleeding. She complained of chronic fatigue, headache, and a general malaise. Upon admission to your institution her hemoglobin level was 7.5 mg/dL. She was scheduled for an abdominal hysterectomy the following day and the surgeon requested three units of red cells to be given prior to the surgical procedure. M had no history of transfusion or pregnancy.

11. Which of the following antibodies remain after completion of the antibody identification (completion of panel antigram)?

A. Anti-Kpa

B. Anti-Lub

C. Anti-Fya

D. Anti-Jkb

12. Given the patient history and all serology results, what is the best hypothesis of the antibody(ies) identity(ies)?
A. Anti-S
B. Anti-K
C. Anti-Cw
D. Anti-M

13. Which of the following antibodies must be ruled out before a final conclusion can be drawn?

A. Anti-Cw
B. Anti-S
C. Anti-E
D. Anti-D

Screen Cell Antigram Rh MNSs PLewis Lutheran Lu Lub Kell Duffv Kidd Panel Antigrann wis Lutheran Rh MNSs Kell Duffy Kidd Patient Results 1000 00 0000000 00 0 02+

Explanation / Answer

11. Which of the following antibodies remain after completion of the antibody identification (completion of panel antigram)?

Answer A. Anti-Kpa

12. Given the patient history and all serology results, what is the best hypothesis of the antibody(ies) identity(ies)?

Answer B Anti-K

13. Which of the following antibodies must be ruled out before a final conclusion can be drawn?

Answer C. Anti -E

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