Glucose is imported into cells by glucose transporters and glucose levels inside

Question

Glucose is imported into cells by glucose transporters and glucose levels inside cells are constantly regulated. What prevents glucose of being exported towards the outside of the cell when glucose levels on the inside are high? a) glucose transporters are unidirectional, they only move glucose molecules from the outside to the intracellular space. b) glucose is maintained in vesicles thus preventing to be exported. c) glucose is imported by passive transport and exported by active transport (requires onse ATP) d) upon intake, glucose is immediately phosphorylated by hexokinase.

Explanation / Answer

Glucose is imported by passive transport and exported by active transport (requires ATP) - Glucose is transported through GLUT (Glucose Transporters) by facilitated diffusion into a cell. But when the concentration of the glucose becomes high - in the case reabsortion in kidney, Na+/K+ pumps export the glucose against the concentration gradient into the bloodstream using ATP. Glucose transporters are not unidirectional theoretically.

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