29. True or False: Equalization of the amount of expression of X-linked genes in

Question

29. True or False: Equalization of the amount of expression of X-linked genes in males and females i accomplished via random X chromosome inactivation in females in ALL species. 30. In cats, the X-linked coat color allele X.encodes black fur and the X-linked coat color allele X encodes orange fur. What genotypes can result in a calico or tortoiseshell coat color (mixed black and orange) in female cats? In male cats? 31. Who proposed that dosage compensation in mammals occurs via inactivation of a single X chromosome in females? 32. True or False: The SRY gene on the Y chromosome encodes the male hormone testosterone. 33. The greater degree of phenotypic variation observed in human females compared to males is explained by what genetic phenomenon?

Explanation / Answer

29: false.

Because dosage compensation is achieved by two means- either supressing expression of one X in female (as in humans) or doubling the expression of X in male (as occurs in drosophila).

30:

Genotype of female: X+Xa

Genotype of male: X+XaY

31: Dosage compensation was proposed by Mary Lyon.

32: false.

Genes for testosterone are on X chromosome. SRY encodes for SRY protein.

33: Random X inactivation.

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