C) Hulllar iu (D) Lactase persistence underwel previously unstudied population o

Question

C) Hulllar iu (D) Lactase persistence underwel previously unstudied population of humans. She sequences 1000 individuals an Q 17: A researcher is studying the distribution of sickle cell anemia in a following statements is most likely to be FALSE (A) Malaria does not exist where these humans live. (B) There (C) Hom is strong purifying selection against the sickle cell allele. ozygous wildtype individuals are more fit than are heterozygous individuals. (D) There is heterozygous advantage for sickle cell allele in this population. 18. Which of the following statements is TRUE (choose one)? (A GWAS can identify whether mutations cause a disease in humans. (B) GWAS is for discovering Mendelian disease genes only. (C) GWAS requires follow-up studies to determine causation vs. association. (D) False positives in GWAS studies are very rare. 19. Which statement regarding trisomy diseases is TRUE? (A) Chromosomes with fewer genes are more likely to experience trison (B) Chromosomes with more genes are most likely to experience trisom (C) All chromosomes are equally likely to experience trisomy (D) There is no way to predict if a chromosome can experience trisomy

Explanation / Answer

1) There is heterozygous advantage for sickle cell allele in this population - Heterozygous advantage is seen when a heterozygote individual has a higher relative fitness in the population. Since, there is not heterozygotes in the mentioned population, it means there is no heterozygous advantage and hence, it can be inferred that particular population had never encountered malaria. Individuals who are heterozygote to sickle cell anemia are resistant to malaria.

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