Help please 20. (BL3) How many products are there in the pathway shown above? a.
ID: 202949 • Letter: H
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Help please
20. (BL3) How many products are there in the pathway shown above? a. Two b. Three c. Four d. Five e Six Active site available in active site used up by eedback Active inhibitionsite no inhibitionAtive Intrmedlate A is halted. binds to allosteric site. Enzyme 4 End product isoleucine) 21. (813) Using the above figure of feedback inhibition, what will happen to Threonine if there is a mutation in Enzyme 4 that prevents it from functioning? a. b. c. d. e. It will continue to be made since it never is acted upon by enzyme 4 It will change directly to isoleucine It will be remade by isoleucine It will build up It will disappear C. b. Enzyme Substrate Competitive Noncompetitive inhibitor inhibitor 22. (BL3) How would a noncompetitive inhibitor interfere with a reaction involving the enzyme shown in the above figure? a. It would bind to a. b. It would bind to b. c. It would bind to o. d. It would bind to d. e. Cannot tell from the information givenExplanation / Answer
21. Option E is correct.
If enzyme 4 is absent, intermediate D can not be synthesized. Since intermediate D is the immediate precursor of Ile, Ile will be depleted in the absence of Enzyme 4.
22. Option B is correct.
A non-competitive inhibitor binds to a site other than substrate binding site and inhibits enzyme function. It can bind to the free enzyme or to ES complex.
A non-competitive inhibitor does not affect Km, but lowers Vmax.
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