16. There are many diseases that are affected by the dysfunction of the rough en

Question

16. There are many diseases that are affected by the dysfunction of the rough endoplasmic reticulum (ER), including Alzheimer's. A dysfunctional ER could result in A. Proteins not translated correctly by free ribosomes. B. Incorrect folding of proteins. C. The lack of a signal sequence on the mRNA of these proteins. D. mRNA of the proteins is not transported from the nucleus to the cytoplasm. E. More than one answer above is plausible. while skeletal muscle cells will 17. Liver cells, which aid in detoxification, will have most likely have A. high amounts of mitochondria; low amounts of mitochondria. B. high amounts of smooth ER; low amounts of smooth ER. C. high amounts of smooth ER; high amounts of mitochondria. D. low amounts of smooth ER; high amounts of mitochondria. E. low amounts of smooth ER; low amounts of mitochondria.

Explanation / Answer

16. B- incorrect folding of proteins

as misfolded or incorrectly folded proteins can not exit ER, and acuumulates their which produces ER stress.

17. high amount of smooth ER, while skeletal muscle cells will most likely have high amounts of mitochondria.

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