Oxytocin, neurotransmitters, and neurohormones can regulate smooth muscle active
ID: 202445 • Letter: O
Question
Oxytocin, neurotransmitters, and neurohormones can regulate smooth muscle actively by _____ the _____ and _____ reticulum membranes, enabling Ca2+ ions to influx and bind to _______. This complex activates myosin light chain kinase (MLCK), and in turn activates _____ ATPase by phosphorylating the light protein chains in the myosin head. These ______ heads can then form cross bridges with actin and subsequently create a shortening. The role of oxytocin in all this is to bind to____--_____ coupled receptors so as to release _____+ from the SR.
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Explanation / Answer
oxytocin, neurotransmitters and neurohormones can regulate smooth muscle actively by depolarising the plasma membrabne and smooth endoplasmic reticulum membranes, enabling Ca+ ions to influx and bind to CALMODULIN. This complex activates myosin light chain kinase and in turn activates MYOSIN ATPase by phosphorylating the light protein chain in myosin head. These phosphorylated heads can then form cross bridges with actin and subsequently create a shortening. The role of oxytocin in all this is to bind to G PROTEIN coupled receptor so as to release Ca+ from the SR.
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