Look at how much points I got to determine answer Sequence analysis of the three

Question

Look at how much points I got to determine answer Sequence analysis of the three alleles and comparison with the wild type sequence showed that the defects Rlag question in these alleles are as follows CYPA1-1: Arg> Stop codon 100 bp upstream from the 3' end of exon 2 CYPA1-2:Cys>Stop codon 30 bp upstream from 3 end of exon 2. CYPA1-3:T> G substitution 2 bp downstream from the 3 end of exon 2 (the carboxy terminus sequence of the CYP1A-3 polypeptide matches the wild type sequence). RNA blot analysis (Northerns) and immunoblot protein analysis (Westerns) of homozygotes for the three different mutant alleles as well as the wild type are shown below Northern Blot Western Blot Interpret blot data above for each mutant allele and select the best interpretation below Quen 13 The mutation in the CYP1A-1 allele: (check al lthat apply) Pores·of100 Select one or more a. Prevents export of the RNA from the nucleus b. Suppresses transcription of the CYP71A1 gene e. Invokes nonsense mediated RNA decay MacBook Air 088a 3 4 5 9

Explanation / Answer

13) the correct options are option (c), (e), (f), (I)

15) the correct option are options (a), (c), (e), (g), (k)

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