32. n early 1980s, Drs. Barry Marshall and Robin Warren were studying patients w

Question

32. n early 1980s, Drs. Barry Marshall and Robin Warren were studying patients with gastritis nflammation of the stomach mucosal lining). Patient biopsies of their stomach lining showed spiral shaped bacteria near inflamed stomach tissue. They also found the bacteria in biopsies from patient with gastric ulcers. The bacterium was named Campylobacter pylori and later renamed Helicobacter pylori. About 80% of individuals infected with the bacteria do not have any symptoms. However, individuals who do develop gastritis have a 15% risk of developing ulcers and-1% chance of developing stomach cancer Using Koch's postulates, indicate in 4-5 sentences how you would specifically and ethically demonstrate that Helicobacter pylori is responsible for gastric ulcers. 5pts

Explanation / Answer

Koch's Postulate hold

Now, isolation of pathogen and its culture in vitro is the easy part. Ethically we cannot infect humans with the same pathogen. In this case, test animals like mice or pig can be used. They can be infected and screened for the symptom and presence of the pathogen.

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