\"You are studying a number of proteins that are present in the nucleus. You fin
ID: 201166 • Letter: #
Question
"You are studying a number of proteins that are present in the nucleus. You find that all the proteins in the nucleus have the following amino acid sequence in common somewhere on the protein: PPKKKRKV. You hypothesize that this sequence is a signal sequence that is used to direct proteins to the nucleus. If you were to add this sequence to a cytoplasmic protein, what would you predict would happen to the protein (if your hypothesis were correct)?"
The protein would be degraded.
The protein would become a carbohydrate.
The protein would be located in the nucleus instead of the cytoplasm.
Nothing would happen--the protein would remain in the cytoplasm.
a.The protein would be degraded.
b.The protein would become a carbohydrate.
c.The protein would be located in the nucleus instead of the cytoplasm.
d.Nothing would happen--the protein would remain in the cytoplasm.
Explanation / Answer
The location of the protein is dependent on the signal sequence a protein contain. The given signal sequence directs the protein to nucleus. If we have the signal sequence to target it to the cytoplasm, the the protein will remain in the cytoplasm and nothing would happen to it. So, the correct option is d.
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