ALL questions must be answered Problem Set Questions: 1) True or False: Most pro

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ALL questions must be answered
Problem Set Questions: 1) True or False: Most protein conformational changes involve breaking and reforming several covalent bonds along the polypeptide chain 2) sidechains on the Fill in the blanks. Soluble proteins have mostly inside and mostly sidechains on the outside. 3) The least restricted and angles are found in polypeptides in which class of secondary structure? a. b. c, d. right-handed helix sheet left-handed helix loop 4) Fill in the blanks. In an helix, the the of residue "i" hydrogen bonds with of residue "i+". 5) Why are helices in naturally occurring proteins almost always right handed? 6) helices have what is known as a helical dipole moment. Explain what this is? would you expect -helices and 310 helices to have these dipoles? why or why not? 7) What is the difference between ribbon, cartoon and cylinder representations of helices?

Explanation / Answer

ANSWER:

5. due to thermodynamic stability by hydrogen bonds.

6. the alignment of dipoles of polypeptide causes this dipole moment. yes, they have dipole moments as their hydrogen bonds orient to the same direction

7. ribbon- shows overall path & organization of protein

cartoon-shows secondary structures representation of a protein

cylinder- represents alpha-helices

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