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Prokaryotic DNA polymerase III: Question 4 options: has a beta subunit that acts

ID: 200622 • Letter: P

Question

Prokaryotic DNA polymerase III:

Question 4 options:

has a beta subunit that acts as a circular clamp to improve the processivity of DNA synthesis.

contains a 5'--> 3' proofreading activity to improve the fidelity of replication.

synthesizes only the leading strand; DNA polymerase I synthesizes the lagging strand.

synthesizes DNA in the 3' --> 5' direction.

does not require a primer molecule to initiate replication.

has a beta subunit that acts as a circular clamp to improve the processivity of DNA synthesis.

contains a 5'--> 3' proofreading activity to improve the fidelity of replication.

synthesizes only the leading strand; DNA polymerase I synthesizes the lagging strand.

synthesizes DNA in the 3' --> 5' direction.

does not require a primer molecule to initiate replication.

Explanation / Answer

answer -Prokaryotic DNA polymerase III: has a beta subunit that acts as a circular clamp to improve the processivity of DNA synthesis. because DNA

polymerase 3 has  3' --> 5' proofreading activity to improve the fidelity of replication, not 5'--> 3'. and it synthesize both leading and lagging stand. also it synthesize DNA in 5'--> 3' direction. and most important DNA polymerase 3 require primer for initiation of replication.

this enzyme extends DNA chain with high processivity (>500 kb of DNA can be continuously synthesized without dissociation of polymerase from template) and high catylatic efficiency.