I need help understanding these questions... 1. Consider a protein that contains

Question

I need help understanding these questions...

1. Consider a protein that contains no ER signal sequence in the N-terminus. It does, however, contain two “start transfer” sequences and one “stop transfer” sequence ( N-term---Start----Stop---Start---C term.) Which of the following statements about this protein is TRUE?

A. The N terminus of the protein will be in the ER
B. The C terminus of the protein will be in the ER
C. It has four membrane-spanning domains
D. Both the N and C termini will be in the ER


2. Which of the following is TRUE concerning nuclear import?

A. Directionality is obtained via GTP hydrolysis
B. It occurs co-translationally
C. Proteins must be unfolded first
D. The signal recognition particle is required


3. What usually stimulates the release of neurotransmitters in a pre-synaptic neuron?

A. A decrease in the calcium ion concentration inside the cell
B. An increase in the chloride ion concentration inside the cell
C. An increase in the calcium ion concentration inside the cell
D. An decrease in the chloride ion concentration inside the cell

Explanation / Answer

1 C. It has four membrane-spanning domains 2 B. It occurs co-translationally 3 C. An increase in the calcium ion concentration inside the cell

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