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During the last S-phase before meiosis in Neurospora, a single mutation occurred

ID: 200162 • Letter: D

Question

During the last S-phase before meiosis in Neurospora, a single mutation occurred in a single nucleotide that resulted in a mismatched A to C base pair, with the A being the mutant nucleotide; C is the wild-type version. This mutation was not repaired before meiosis. In the final 8 asco spores, how many spores have the base pair G-C (wild type), the base pair A-C (mismatch) and the base pair A-T (mutant)? Remember, there is an extra S-phase after meiosis in Neurospora.

Question 9 options:

8, 0, 0

7, 1, 0

7, 0, 1

6, 1, 1

6, 0, 2

5, 2, 1

4, 0, 4

4, 2, 2

8, 0, 0

7, 1, 0

7, 0, 1

6, 1, 1

6, 0, 2

5, 2, 1

4, 0, 4

4, 2, 2

Explanation / Answer

I believe the correct option to be 6,0,2 because when meiosis occurs and the gene is replicated again, A-C will break and both will form their complementary AT and GC. So, the end result should come in the above mentioned ratio.

Thank you. Leave a comment if you feel I am wrong.

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