Which of the following mutations is most likely to have the greatest impact on t

Question

Which of the following mutations is most likely to have the greatest impact on the phenotype of a human?

a. Substitution in a non-protein coding region

b. Insertion/Deletion of a single base pair in a protein coding region

c. They all are likely to have the same impact on phenotype

d. Substitution in a protein coding region

a. Substitution in a non-protein coding region

b. Insertion/Deletion of a single base pair in a protein coding region

c. They all are likely to have the same impact on phenotype

d. Substitution in a protein coding region

Explanation / Answer

b.Insertion/deletion of a single base pair in a protein coding region.Because it will lead to change in all the codon after this and result in different amino acid synthesis.

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