2.If fumarate levels accumulate due to the reason laid out in the preceding ques

Question

2.If fumarate levels accumulate due to the reason laid out in the preceding question, the reaction catalyzed by which enzyme can be reversed by mass action to eliminate fumarate? What intermediate will then accumulate as the result of this reverse reaction? A. Malate dehydrogenase; malate B. Malate dehydrogenase; oxaloacetate C. -ketoglutarate dehydrogenase; -ketoglutarate D. -ketoglutarate dehydrogenase; succinyl-CoA E. Succinyl-CoA synthetase; succinyl-CoA F. Succinyl-CoA synthetase; succinate G. Succinate dehydrogenase; succinate H. Succinate dehydrogenase; succinyl-CoA

Explanation / Answer

G- succinate dehydrogenase, succinate .

Note - this reaction can be reversed in accumulation of fumurate as this is reversible enzyme succinyl dehydrogenase which produce its former substrate as product later on reversle .

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