6. The \'high dose\' strategy of managing the evolution of pesticide resistance
ID: 198065 • Letter: 6
Question
6. The 'high dose' strategy of managing the evolution of pesticide resistance in insect populations a. is likely to fail when the biochemical mechanism underlying resistance is target site insensitivity, b. is likely to fail when the biochemical mechanism underlying resistance is detoxification, because c. is likely to fail when there is persistent immigration of susceptible individuals to the targeted d. is likely to fail when the individuals who are heterozygous for a resistance trait (genotype RS) are e. none of the above is true because such a mechanism of resistance is often expressed as a dominant trait such a mechanism of resistance is often expressed as a dominant trait populations killed by the applied dose of the pesticideExplanation / Answer
Pesticide resistance among the target insects is one of the major problems faced by scientist developing pesticides. Many insects have become resistant to such an extent that no matter what the dose of the pesticide, it is ineffective on the target population. Many factors might contribute to this but the main factor is mutation in a gene which helps the insect to detoxify the chemical in its gut. Several detoxifying enzymes are developed in such pests which help to detixify the pesticide and get rid of the toxins. Such mutant breeds then become dominant by the process of natural selection as the gene is transferred to the next generations.
A very good example of the development of resistance to pesticides by detoxification is that of the female anopheles mosquito. This mosquito is a vector for malaria parasite and it became resistant to DDT which was used to kill its larvae. [ Use of DDT is banned now due to its severe damaging effec on the environment] .
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