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the the two reactions described in questions 2 and 3. After the substrate G3P en

ID: 197706 • Letter: T

Question

the the two reactions described in questions 2 and 3. After the substrate G3P enters active site, a covalent bond forms between G3P and the R group on the amino acid cysteine, which is located in the active site. enzyme residue enzyme (Cys residue) H-0-C-H + NADH +H H-C-OH The reaction of the intermediate with NAD+ results in the formation of NADH and a thioester intermediate. What is the function of this thioester intermediate and how does its formation impact the enzyme? Mark ALL of the correct statements. The thioester intermediate preserves much of the free energy released in the first reaction (Redox reaction), thereby facilitating the formation of 1,3 BPG to occur in the second reaction. The thioester intermediate induces a conformation change that alters the enzyme specificity and prevents any other molecules from entering the active site. The enzyme is permanently changed by the formation of the covalent bond between the cysteine in its active site and the substrate. Although the enzyme G3P Dehydrogenase changes the activation energy, it does not change the final equilibrium (ratio of products to reactants). None of the above answers are correct.

Explanation / Answer

I am not sure but either its the last one i.e none of the above answers are correct or it is the first one, i.e the thioesters immediately preserves much of the energy.

sorry cant be of more help. If you find the answer, plz make sure to comment down below as well.