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Evaluate the graph below to answer the following question: **The only informatio

ID: 197523 • Letter: E

Question

Evaluate the graph below to answer the following question:
**The only information provided is in the description below, that says figure 10**, the circles are not defined there

In Fig. 10, the growth rates of the original (ancestral) resistant mutation strains are presented above the "R" on the x-axis. Estimate the effect of antibiotics on the growth rate of the original H594Y mutant.

a) Its growth rate in the presence of antibiotics is zero. S 0.8 D 0.6 8 0.4 0.2 REE+M REE+M REE+M R E E+M H594Y F596L WV630-631L W443R

Explanation / Answer

A is not the correct answer because as you can see in the scale of the "y" axis, the white square growth rate is 0.25, not zero.

D is also incorrect because there is a clear difference between the white and the black square, they don´t have the same value for the growth rate so there is an effect with the antibiotics even though is a resistant strain.

So to see how big the effect is, we have:

0.25 growth rate of the strain exposed to antibiotics

0.6 growth rate of the strain without antibiotics.

So 0.6 is the biggest growth rate we have for this strain, we polarize this value to 1:

0.6 is to 1 as 0.25 is to x:

0.25 * 1 / 0.6 = 0.41, or 41%

The correct answer is c.

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