Hi there I am looking for some help with my toxicology study guide questions 15.

Question

Hi there I am looking for some help with my toxicology study guide questions

15. Many toxicants cause the formation of Heinze bodies. Heinze bodies are the result of damage to:

A) Eosinophils

B) Neutrophils

C) Platelets

D) Hemoglobin

16. In which of the following locations of the heart would one NOT find spontaneous depolarization?

A) SA node

B) Myocardium

C) AV node

D) Bundle of his

E) Purkinje fibers

17. Which of the following is most likely NOT a cause of myocardial reperfusion injury?

A) Cellular pH fluctuations

B) Damage to the sarcolemma

C) Generation of toxic oxygen radicals

D) Calcium overload

E) Inhibition of the electron transport chain

18. Cardiac glycosides:

A) Increase the activity of the Na+/K+-ATPase

B) Make the resting membrane potential more negative

C) Can have sympathomimetic and parasympathomimetic effects

D) Decrease ventricular contractility

E) Increase AV conduction

19. Which of the following is NOT a common cardiotoxic manifestation of cocaine abuse?

A) Parasympathomimetic effects

B) Myocardial infarction

C) Cardiac myocyte death

D) Ventricular fibrillation

E) Ischemia

20. Which of the following is NOT a common mechanism of vascular toxicity?

A) Membrane disruption

B) Oxidative stress

C) Bioactivation of toxicants

D) Reduction and accumulation of LDL in endothelium

E) Accumulation of toxicants in vascular cell

Explanation / Answer

15. D) Hemoglobin

16. B) E) Purkinje fibers

17. A) Cellular pH fluctuations

18. D) Decrease ventricular contractility

19. D) Reduction and accumulation of LDL in endothelium

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