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Question 8 (1 point) What is the twist of relaxed B-DNA? Question 8 options: 1 b

ID: 193577 • Letter: Q

Question

Question 8 (1 point)

What is the twist of relaxed B-DNA?

Question 8 options:

1 bp/turn

105 bp/turn

10.5 bp/turn

0 bp/turn

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Question 9 (1 point)

Which of the following statements about DNA supercoiling is FALSE?

Question 9 options:

The linking number (Lk) of a closed-circular DNA molecule can be changed only by breaking one or both strands.

DNA of all organisms is overwound (i.e., positively supercoiled).

In a nucleosome, supercoiled DNA is wrapped around histone proteins.

Topoisomerase I relaxes DNA that is highly negatively supercoiled.

Supercoiling allows for the extreme compaction required for DNA to fit in a cell

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1 bp/turn

105 bp/turn

10.5 bp/turn

0 bp/turn

Explanation / Answer

Que 8

Ans:

The twist of relaxed B DNA is: 1 bp/turn.

Explanation:

- Twist represents the number of turns in DNA helix in a given fragments of DNA.

- Relaxed DNA that is not supercoiled has a twist of +1 for every repeat of the double helix.

Que 9

Ans:

The following statement about DNA supercoiling is FALSE: DNA of all organism is overwound (i.e. positively supercoiled).

Explanation:

- Negative supercoiling plays an important role in nearly all organisms.

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