Question 11 (1 point) Type ________ topoisomerase introduces negative supercoils

ID: 193552 • Letter: Q

Question

Question 11 (1 point)

Type ________ topoisomerase introduces negative supercoils in DNA while type ________ topoisomerase relaxes supercoil structures.

Question 11 options:

II ; I

I ; II

I : I

II ; II

Save

Question 12 (1 point)

How does a DNA gyrase release positive supercoils that accumulate ahead of the DNA replication fork?

Question 12 options:

Without the help of ATP, it breaks two strands of DNA at a time allowing the complementary strand to pass through.

It breaks two strands at a time in an ATP fueled reaction passing another region of the duplex through the resulting gap.

Without the help of ATP, it breaks one strand of DNA at a time allowing the complementary strand to pass through.

It breaks one strand of DNA at a time, in an ATP fueled reaction, allowing the complementary strand to pass through.

Save

Question 13 (1 point)

Which amino acids at the active site a type II topoisomerases forms a covalent bond with DNA?

Question 13 options:

Aspartate

Tyrosine

Serine

Threonine

Save

II ; I

I ; II

I : I

II ; II

Type II topoisomerase introduces negative supercoils in DNA

while type I topoisomerase relaxes supercoil structures.

Option a is the answer

DNA gyrase is an ATP dependent enzyme which can create nicks in both

the strands of DNA at the same time.

Option b is the answer.

Topoisomerase II is known to initiate DNA cleavage by forming covalent bond with of the active site of tyrosine .

Option b is the answer

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.