Drugs \'R Us has developed 2 new drugs can diffuse easily through the e patch in

Question

Drugs 'R Us has developed 2 new drugs can diffuse easily through the e patch in this systeagesic (pain killing) drugs. Both are administered trans-dermally, via a a semi-permeable membrane, as does your skin. Therefore these membrane and skin and eventually enter your blood stream.) 1) The two new drugs share the same Away has a molecular weight of s00 g/M; Relief X has an MW of take for the quickest relief of your pain? Why? mechanism of action but they have different molecular weights. Pain 250 E/M. Which drug would you chose to 2) If you increase the dose (gra drug on the patch will the time it takes the drug to enter your blood stream increase or dere ms of drug/Kilogram of body weight; this equates to concentration) of either drug is placed on each patch, would you choose a 1 inch square or 4 3) Assuming the same concentration of inch square patch if you wanted fast relief? Why? 4) It is a hot summer day and you are very thirsty. You want to make some ice tea fast. Which method would Making Sun tea: Sun tea is made by placing the tea bag in a container and sitting the container in a steeping your tea bag in boiling water, then stirring in cold water and ice to cool down the mixture provide the tea faster? Explain. sunny spot or

Explanation / Answer

1) We know that rate of diffusion is inversely proportional to the square root of mass as per Graham's Law of diffusion. Hence ofr faster relief we need faster rate of diffusion, thue we'll use Relief X Mol Wt = 250g/mol.

2) As the concentration increases, rate of diffusion increases. Hence if the concentration of the drug increases the time taken by it to enter the body will decrease.

3) Greater the surface area, more is the diffusion. Hence for faster relief, we'll use 4- inch square patch.

4) We'll use the second method. As the temprature difference increases, rate of heat transfer will increase. Also, in boiling water the tea bag will release its content faster, hence ice tea will get prepared faster and will be more cooler.

5) If the sports drink has more solute it will increase the osmotic pressureof the blood and hence the cells will be in a hypertonic solution, because of which they'll lose more water to become isotonic causing more dehydration of cells and cell shrinkage. To rehydrate cells sports drink should have less solute, so that cells get hydrated.

6) This intavenous fluid has more solute content than brain cells, which leads to release of brain cell fluid, thus relieving the pressure. The excess fluid is carried to the kidneys and is removed from the body by urination.

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