Paragraph Assumptions . There are approximately 3,000,000,000 base pairs in the
ID: 193412 • Letter: P
Question
Paragraph Assumptions . There are approximately 3,000,000,000 base pairs in the mammalian genome (genes constitute only a portion of this total) . There are approximately 10,000 genes in the mammalian genome. . A single gene averages 10,000 base pairs in size Only 1 out of 3 mutations that occur in a gene result in a change to the protein structure In the mammalian genome: 1. How many total base-pairs are in all the mammalian genes? 2. What proportion (%) of the total genome does this represent? 3. What is the probability that a random mutation will occur in any given gene? 4. What is the probability that a random mutation will change the structure of a protein?Explanation / Answer
Q.1
Ans: Total base pair= 10000 gene × 1000bp/gene= 100000000
Q.2
Ans: Total percent of genome= 100000000/3000000000×100=3.33%
Q.3
Ans: Single gene / all pair in genome= 10000bp/
3000000000bp=1/300000
Q.4 Random mutation probability in the change the structure of a protein: (1/30000)×1/3=1/90000
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