1NQUIZITIVE Chapter 5: Cell Biology of Bacteria and Eukaryotes sazz e Page(s) 13

Question

1NQUIZITIVE Chapter 5: Cell Biology of Bacteria and Eukaryotes sazz e Page(s) 132-135 5.3 The Bacterial Cell wall and Outer Layers Complete the following passage about bacterial characteristics and antibiotic efficacy. Drag wordfs) below to fill in the bloank(s) in the passage. Gramcells r more susceptible to peniclin than Gramcells because the thick cell of Gram-positive cells are critical for their function. Gram cellsalso g which excludes small molecules, such as contain an outer Although both Gram-negative and Gram-positive cells encode antimicrobial efflux pumps, they ane different pumps and target different target certain bacteria. For example, ethambutol is a highly specific antibiotic that only targets acid These differences allow some antibiotics to fast bacteria. chitin! positive" specifically! Gram-positive + membrane +1 peptidoglycan + nonspecifically antibioticswater cellulosewalsnegative membranes here to search 8

Explanation / Answer

Gram positive cells are more susceptible to penicillin than gram negative cells because thick peptidoglycan cell walls of gram positive cells are critical for their function. Gram negative cells also contains outer membrane which excludes small molecules such as antibiotics.

Although both gram negative and gram positive cells encode antimicrobial efflux pumps they are different pumps and target different antibiotics. These differences allow some antibiotics to target certain bacteria specifically for example ethambutol is highly specific antibiotic that only target acid fast bacteria.

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