20. Which of the following is correct concerning the a. This interaction is dram
ID: 192652 • Letter: 2
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20. Which of the following is correct concerning the a. This interaction is dramatically affected by extremes in plhi. b. This is an example of a hydrophobic interaction. side-chain to side-chain In this interaction the oxygen in the Serine side-chain is the "acceptor and the N-H of Asn is the "donor" of the Hydrogen bond Once this interaction is formed, these side-chains can no longer interact favorably with water This is an example of a salt bridge. d. e· 21. In the text, the following is a sentence in the Biochemical Connections topic on Sickle Cell Anemia. "The glutamic acid in the sixth position (of the chain) in normal Hb is replaced with HbS." This information is considered as part of the a valine residue in a. . structure of hemoglobin. c. Tertiary d. Quaternary b. Secondary Consider the oxygen saturation curve for myoglobin and hemoglobin under various conditions to answer the next two questions. Ovygen Saturation 22. The curve that corresponds to the oxygenation of Myoglobin is curve B. c. C d. D 23. Consider that Hemoglobin under normal conditions at pH 7.40 is curve C. Which curve corresponds to Hemoglobin under conditions when a person is chocking, which means higher Poe and lower pH? 62 | A. B. D. d. C. (choose if Hemoglobin is not affected by changes in Poco and pH) 24. Which of the following is correct concerning the protein Collagen? a. Collagen is the major protein in wool. 6 Collagen is the major structural protein in animals and found in connective tissue and bone. c. Collagen is the major protein in silk. d. Collagen is composed of mostly bulky aromatic amino acid residues. Collagen has good nutritional value because it contains all dietarily essential amino acids. 25. "Site ic residue in an enzyme (protein). Which of the following amino acid residue substitutions would bly have the most dramatic adverse (negative) effect on the structure and function of an enzyme? a. Asn changed to an Gin b. lle changed to a Val Lys changed to an Arg Glu changed to a Phe None of the substitutions above would affect the structure and function of an e. enzyme.Explanation / Answer
22. Answer is option a because as the pressure drops and myoglobin and haemoglobin moves towards the tissues myoglobin still maintains its high affinity for oxygen while haemoglobin not because of its coperativity suddenly loses its affinity therefore making it better transporter of oxygen than myoglobin
23. Answer is option C because In high CO2 and acidic pH,tissues require more oxygen so Oxyhaemoobin will dissociate and curve shifts to right side.
Option A is incorrect as it shows hyperbola curve of Myoglobin which has higher affinity for oxygen than haemoglobin
Option B is incorrect as it shows sigmoidal shape of oxygen.
24.answer is option B as collagen is a fibrous protein which is the most abundant protein found in animals for strenghthening and major component of matrix of connective tissue and composed of three polypeptide strands called as alpha chains which has a conformation of left handed helix.
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