Enzymes (or their production) are often regulated in a negative or positive way,
ID: 192326 • Letter: E
Question
Enzymes (or their production) are often regulated in a negative or positive way, depending on whether they are related to anabolic (building) or catabolic (breaking down) reactions. Please describe, in your own words, why excess of products might inhibit enzymatic activity for anabolic reactions but why excess of reactants might stimulate enzymatic activity for catabolic reactions. This question is pretty complex, so take your time to develop your thoughts prior to typing your answer. The best answers should incorporate aspects of bioenergetics, genetic expression and cell biology.
Explanation / Answer
In anabolism, which is construction process and input of ATP energy need. The enzymes that catalyze these anabolic process are mostly multimeric or allosteric in nature. That means, they possess another regulatory site, in addition to the active site. Due to this, they inhibited by end products.
Where as in catabolism, where, Breakdown of complex molecules into simple ones release energy. These reactions are catalyze by Simple or monomeric enzymes. They only contain Active site, where substrate bind and promotes catalysis . No regulatory site. So no other molecules regulation.
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