It’s bioengineering lap , I need the goal of this lab, interpreation and conclus
ID: 191627 • Letter: I
Question
It’s bioengineering lap , I need the goal of this lab, interpreation and conclusionLab 2 miniature assembly made up of a aped center channel allows Lab 2: BodyChips Brain-on-chip (BOC) modules are coverslip sealed to the bottom of the 3D printed chamber we eva mold design is both functional and morphological. Functionally, the narro controlled mixture of the two precursor components that synthesize the biomaterial micture often results in a non-uniform 'pellety' matrix. The BOC design, as it must have chemical and material properties within the brain. Without an appropriate 3D environment, cells encapsulate created within a luated in lab 1. The proprietary H-sh matrix. Rap biomaterial matrix plays a critical role in the that mimic the natural environment of cells d within the BOC, such as the neurons, cannot form the necessary connections, known as neurites, for cell-to-cell communication, or otherwise behave as they would in vivo. In addition, the design features an optically clear coverslip bottom, which provides a window through which optical imaging and analysis of the BOC can be performed. The terms of our subcontract require that we assemble the BOC chamber, test for function, evaluate feasibility of optical imaging, and evaluate the assembly for any contaminants that may present a challenge to ultimately arriving at a fully functional BOC Rapid prototyped 'chips' must be prepared for further testing. Preparation involves sealing the chamber with a clear 'coverslip' or thin window through which cells and the gel matrix can be visualized. This is accomplished using a silicone sealant. This sealant can be slow to harden, so the window is further reinforced with hot glue. To retain functionality, the device must maintain flow through the small central channel, must not leak, and must be easy to image through. The exact tests used for this validation are left to the discretion of the research team. Today you will use .Your set of laser cut BOCs .Coverslip (22 x 22 mm) Silicon adhesive .A glue gun and glue stick(s) 15 mL conical tube with distilled water A set of pipettes (20 , 200 , 1000 A set of pipette tips for the pipettes listed above A water squirt bottle .Clear plastic beaker for temporary sharps waste . Plastic dish Marker
Explanation / Answer
Goal :the goal of this lab. is to design a BOC, that could simulate real brain for evaluating effect of various chemical and biological agents, or drugs on brain cells.
Interpretation :while designing BOC, cells are ensured environment as natural as possible (3D) platform, so that they behave naturally. Then cells are studied for different toxicity tests.
Conclusion :In this lab, we developed a BOC and tested it for all features. It did not pass all the quality control tests as it failed to maintain a constant flow through central channel. So this lab is to be repeated.
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