On average, what fraction of the genome in the following pairs of humans wou cro
ID: 190002 • Letter: O
Question
On average, what fraction of the genome in the following pairs of humans wou crossing over took place? For the purposes of this question only, we will ignore the special case of the X and Y sex chromosomes and assume that all genes are that the uncle and niece are related by a sibling and not by marriage alone. ld be exactly the same if no on non-sex chromosomes. Also, assume Father and child 1/2 Mother and child 1/2 Full siblings 1/2 Incorrect Whereas other genomic fractions may also be incorrect, the fraction for the uncle and niece is Half siblings 1/4 cifically incorrect. The uncle is directly related to his niece by his sibling. Uncle and niece First, calculate the fraction of the genome shared between the uncle and his sibling, who is one of the niece's parents. Then, calculate the fraction of the genome shared between the niece's parent and the niece. Last, multiply these two fractions together to obtain the fraction of the genome shared by these two individuals Grandparent and grandchild 3/4 0 1/4 1/2 3/4 1 O Previous & Give Up & View Solution # Try Again O Next ExitExplanation / Answer
Generation 1: grandfather A1A2 × grandmother B1B2
Generation 2: A1B2 A1B1 A2B1 A2B2
Suppose A1B2 is father in generation 3
Generatio 3: father A1B2 × mother C1C2
Generation 4: A1C1 A1C2 B2C1 B2C2
So, A1C1 matches with his/her father/mother( A1B2/C1C2) =(50+50)/2=50 =1/2
A1C1 matches with full siblings (100+50+50+0)/4=50 = 1/2
Where 100 with own, 50 with A1C2 as only A1 matches, 50 with B1C1 where only C1 matches and 0 with B2C2
A1C1 matches with its grandparent (50+0)/2 = 25 = 1/4
Only A1 with grandfather
A1C1(niece) with his uncle (50+50+0+0)/4= 25 = 1/4
Matches 50% with A1B2 and A1B1 of generation 2...where among 4 uncles one is father
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