The proinsulin molecule is made of 3 peptide chains (A,B, and C) whereas the act
ID: 18910 • Letter: T
Question
The proinsulin molecule is made of 3 peptide chains (A,B, and C) whereas the active insulin molecule is made up of just the A and B chain. Rates of mutation have been measured for each chain. The observed rate of mutation of the C peptide chain is greater than the mutation rate of the A and B chain. This pattern is best explained by:
a) The C peptide is not translated thus mutations build up
b) Selection causes greater mutation within the C chain
c) While mutations occur in the A and B chains they have no effect
d) All of the above
e) None of the above
Explanation / Answer
c) While mutations occur in the A and B chains they have no effect
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