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HARDY-WEINBERG 113 TABLE 10.3. Collared lizards in the Ozark region. Generation

ID: 188755 • Letter: H

Question

HARDY-WEINBERG 113 TABLE 10.3. Collared lizards in the Ozark region. Generation 1 Phenotype Orange Yellow Blue AzA 27 Total Number of individuals Observed genotype frequencies Allele frequencies Expected genotype frequencies Are these lizards in Hardy-Weinberg equilibrium (yes/no)? Generation 2 Phenotype Genotype Number of individuals Observed genotype frequencies Allele frequencies Expected genotype frequencies Are these lizards in Hardy-Weinberg equilibrium (yes/no)? Generation 3 Phenotype Genotype Number of individuals 34 29 =90 1.0 =1.0 = 1.0 Yellow A1A2 18 Total Orange AIAI 23 Blue AzA2 21 = 1.0 =1.0 =1.0 Blue Total Orange A Ai 24 Yellow A A2 16 = 74 34 Observed genotype frequencies Allele frequencies = 1.0 Expected genotype frequencies Are these lizards in Hardy-Weinberg equilibrium (yes/no)P

Explanation / Answer

1. Generation 1

Generation 1

Phenotype

Orange

Yellow

Blue

Total

Genotype

A1A1

A1A2

A2A2

Number of individuals

34

29

27

=90

Observed genotype frequencies

34/90=0.377

29/90=0.322

0.3

=1.0

Allele frequencies

p=0.539

q= 0.461

=1.0

Expected genotype frequencies

0.29

0.5

0.21

=1.0

Are these lizards in Hardy-Weinberg equilibrium= Yes

For Allele frequencies and observed genotype frequencies

There are two A1 alleles in A1A1 = 34 X 2= 68

There are one A1 alleles in A1A2= 29

Ozark lizards are diploid.

Frequency of allele A1 in generation 1= (p= 68+29)/90+90= 0.539

Frequency of allele A2 in generation 1= q= 1-p= 1-0.539=0.461

For Expected Frequencies:

The Hardy Weinberg equation is given as:

p2+2pq+q2=1

p2 = frequency of the homozygous genotype A1A1, q2 = the frequency of the homozygous genotype A2A2, and 2pq = frequency of the heterozygous genotype A1A2.

Expected frequency of A1A1= p2= 0.539 X 0.539= 0.291

Expected frequency of A1A2= 2pq= 2X 0.539 X 0.461= 0.5

Expected frequency of A1A2= q2= 0.461 X 0.461= 0.213

Chi-square Test:

Oberved

Expected

(O-E)

(O-E)2

(O-E)2/E

A1A1

0.3777

0.29

0.0877

0.007691

0.026522

A1A2

0.322

0.5

-0.178

0.031684

0.063368

A2A2

0.3

0.21

0.09

0.0081

0.038571

Total

0.9997

1

-0.0003

0.047475

0.128461

Degree of freedom= Number of genotypes-1= 3-1=2

Probability of chi square at d.f 2= 0.93200= 93.2%

A Chi Square value between 1%-5% should allow you to reject the null hypothesis. However, 93.2% is a large P Value. Hence, the null hypothesis is accepted. The frequencies are in Hardy-Weinberg equilibrium.

2. Generation 2

Generation 1

Phenotype

Orange

Yellow

Blue

Total

Genotype

A1A1

A1A2

A2A2

Number of individuals

23

18

21

=62

Observed genotype frequencies

23/62=0.37

18/62=0.29

21/62=0.34

=1.0

Allele frequencies

p=0.52

q= 0.48

=1.0

Expected genotype frequencies

0.27

0.5

0.23

=1.0

Are these lizards in Hardy-Weinberg equilibrium= Yes

For Allele frequencies and observed genotype frequencies

There are two A1 alleles in A1A1 = 23 X 2= 46

There are one A1 alleles in A1A2= 18

Ozark lizards are diploid.

Frequency of allele A1 in generation 1= (p= 46+18/62+62= 0.52

Frequency of allele A2 in generation 1= q= 1-p= 1-0.52=0.48

For Expected Frequencies:

The Hardy Weinberg equation is given as:

p2+2pq+q2=1

p2 = frequency of the homozygous genotype A1A1, q2 = the frequency of the homozygous genotype A2A2, and 2pq = frequency of the heterozygous genotype A1A2.

Expected frequency of A1A1= p2= 0.52 X 0.52= 0.27

Expected frequency of A1A2= 2pq= 2X 0.52 X 0.48= 0.5

Expected frequency of A1A2= q2= 0.461 X 0.461= 0.23

Chi-Square Test:

Oberved

Expected

(O-E)

(O-E)2

(O-E)2/E

A1A1

0.37

0.27

0.1

0.01

0.037037

A1A2

0.29

0.5

-0.21

0.0441

0.0882

A2A2

0.34

0.23

0.11

0.0121

0.052609

Total

1

1

-2.8E-17

0.0662

0.177846

Degree of freedom= Number of genotypes-1= 3-1=2

Probability of chi square at d.f 2= 0.9150= 91.5%

A Chi Square value between 1%-5% should allow you to reject the null hypothesis. However, 91.5% is a large P Value. Hence, the null hypothesis is accepted. The frequencies are in Hardy-Weinberg equilibrium.

3. Generation 3

Generation 1

Phenotype

Orange

Yellow

Blue

Total

Genotype

A1A1

A1A2

A2A2

Number of individuals

24

16

34

=74

Observed genotype frequencies

24/74=0.32

16/34=0.22

34/74=0.46

=1.0

Allele frequencies

p=0.43

q= 0.57

=1.0

Expected genotype frequencies

0.19

0.49

0.33

=1.0

Are these lizards in Hardy-Weinberg equilibrium= Yes

For Allele frequencies and observed genotype frequencies

There are two A1 alleles in A1A1 = 24 X 2= 48

There are one A1 alleles in A1A2= 16

Ozark lizards are diploid.

Frequency of allele A1 in generation 1= p= 48+16/74+74= 0.43

Frequency of allele A2 in generation 1= q= 1-p= 1-0.52=0.57

For Expected Frequencies:

The Hardy Weinberg equation is given as:

p2+2pq+q2=1

p2 = frequency of the homozygous genotype A1A1, q2 = the frequency of the homozygous genotype A2A2, and 2pq = frequency of the heterozygous genotype A1A2.

Expected frequency of A1A1= p2= 0.43 X 0.43= 0.19

Expected frequency of A1A2= 2pq= 2X 0.57 X 0.43= 0.49

Expected frequency of A1A2= q2= 0.461 X 0.461= 0.33

Chi-Square Test:

Oberved

Expected

(O-E)

(O-E)2

(O-E)2/E

A1A1

0.37

0.19

0.18

0.0324

0.170526

A1A2

0.29

0.49

-0.2

0.04

0.081633

A2A2

0.34

0.33

0.01

0.0001

0.000303

Total

1

1.01

-0.01

0.0725

0.252462

Degree of freedom= Number of genotypes-1= 3-1=2

Probability of chi square at d.f 2= 0.881= 88.1%

A Chi Square value between 1%-5% should allow you to reject the null hypothesis. However, 88.1% is a large P Value. Hence, the null hypothesis is accepted. The frequencies are in Hardy-Weinberg equilibrium.

Generation 1

Phenotype

Orange

Yellow

Blue

Total

Genotype

A1A1

A1A2

A2A2

Number of individuals

34

29

27

=90

Observed genotype frequencies

34/90=0.377

29/90=0.322

0.3

=1.0

Allele frequencies

p=0.539

q= 0.461

=1.0

Expected genotype frequencies

0.29

0.5

0.21

=1.0