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4) 2 points. The ability to taste the chemical compound PTC (phenylthiocarbamide

ID: 188216 • Letter: 4

Question

4) 2 points. The ability to taste the chemical compound PTC (phenylthiocarbamide) is coded for by a single gene with two alleles. Let T stand for the allele that codes for tasting and t for the allele that codes for non-tasting. This allele exhibits complete dominance, such that heterozygotes can also taste PTC. Suppose that out of a population of 100 students, 70 are tasters. Estimate the allele frequencies and the frequencies of TT, Tt and tt genotypes in the population. Show all your work, and clearly state your logic and any assumptions you make in estimating the frequencies

Explanation / Answer

Dominant = Tasting = TT or Tt

Recessive = Non-tasting = tt

Total population = 100

Tasters = TT + Tt = 70

Frequency of tasters = 0.7 or 70%

Non-tasters = 100 - 70 = 30

Frequency of non-tasters = 0.3 or 30%

If we assume that the population is in H-W equilibrium,

q^2 = 0.3

q = 0.547

p = 1 - 0.547 = 0.452

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