ich of the following statements about insulin manufacturing is not true? Diabeti

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ich of the following statements about insulin manufacturing is not true? Diabetics used to have to inject themselves with insulin that had been purified from the pancreas of either cows or pigs. Bactena are able to express repro nsulin and process this peptide into rs In Natural ins A proline converted to an aspartic acid keeps insulin from clumping b. ulin forms hexamers, which causes the hormone to clump. e. Recombinant insulin is expressed as two mini-genes. cently discovered autotransporter proteins of bacteria: Transport themselves without using any secretory system. 18. The re a. Ar e able to cross membranes because they are very small proteins. uire the Type IlII secretory system to cross the bacterial outer membrane d. Require the BAM complex to cross the bacterial outer membrane. e. Rely on attached lipid molecules to function. Further Reading in, D. S. (2012). Therapeutic proteins. Methods in Molecular Biology (Clifton, N. J.), 899, 1-26. be A. C Haitjema, C. H., Guarino, C., Çelik, E., Endicott, C. E., Reading, C. A., et al. (2011). Production of enory and extracellular N-linked glycoproteins in Escherichia coli. Applied and Environmental Microbiology, 77, -88 ing W.S, Sauri, A, & Luirink, J. (2010). Extracellular production of recombinant proteins using bacterial auto- aspoters. Current Opinion in Biotechnology, 21, 646-652. adarajan, V, & Weis, M. A. (2012). Design of non-standard insulin analogs for the treatment of diabetes mel- Curent Diaberes Reports, 12, 697-704 (2Opportunities and challenges for the baculovinus espression system. Joumial of Inweretrate V. (2012). Emerging technologies for making glycan-defined glycoproteins, ACS Chemical (2012), Prevalence, biogenesis, and functionality of the serine protease autotransporter n. Z. T, & Robinson, A. S. (2012). Recombinant protein expression and purification a compre nnalian cell protein expression for biopharmaceutical production Biotechmology Adunces, 30. 107 (Suppl), S3-S15. ing L X., &Lomino;, & Brockm loins (Basel), 5, 25-48. n alhinity tags and microbial applications. Biotechnology lournal, 7,620-634

Explanation / Answer

17. Which of the following statement about diabetics is not true...

a) Bacteria are able to express preproinsulin and process this peptide into insulin..

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