7. The following pedigree shows inheritance of the inability to smell Pseudomona

Question

7. The following pedigree shows inheritance of the inability to smell Pseudomonas bacteria and the inability to roll the tongue into a U-shape Inability to roll the tongue is an autosomal recessive trait. Use A/a for smelling/non-smelling and R/r for rolling/non-rolling inability to roll tongue 10 Consider the inability to smell Pseudomonas and complete the following conclusions (ignoree X-inactivation) (0) The data are consistent/inconsistent with an autosomal dominant mode of inheritance because (ii) The data are consistent/inconsistent with an X-linked recessive mode of inheritance because (ii) The data are consistent/inconsistent with an X-linked dominant mode of inheritance because (b) If the two genes are assorting independently, what is the probability that the first child born to lll-4 and lll-5 will be a non-smeller, non-roller?

Explanation / Answer

It is concluded that the pedigree created for inability to smell Pseudomonas showed this inability to be recessive trait and as males are more affected so it is X linked recessive. Therefore:

i) the data are not consistent with autosomal dominant mode of inhertance.

ii) the data are consistent with an X linked recessive mode of inheritance.

iii) since the trait is not transferred from father to son, so the data is also not consistent with an X linked dominant mode of inheritance.

b) If the two genes are assorted independently, there is 50% chance that the child born would be non smeller and non roller.

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