18. The allelic series for an autosomal gene affecting guinea pig coat color is:
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Question
18. The allelic series for an autosomal gene affecting guinea pig coat color is: CCR cCA where c is black, c is sepia, cR is russet, cC is cream and cA is albino. If you cross individuals of the genotype: cc x cc what phenotypic distribution do you expect in the offspring? 19. In order to map the Drosophila genes Bar eye (B), miniature wings (m) and singed bristles (sn), you would make a cross between a female heterozygous for all three traits and a male of what genotype? NB: use proper genetic notation. 20. You are trying to identify the location of a gene for herbivore resistance in rice. After screening a population of 513 plants with 722 microsatellite loci, and conducting a maximum likelihood analysis, you generate the LOD score plot shown below. Chr B Chr C Chr D Chr E Chr F Chr G Chr H chromosome or chromosomes, could a gene contributing to the phenotype of herbivore resistance be located?Explanation / Answer
18. here, CB is the most dominant allele and on other hand CC is most dominant allel. when we crossee CS CR and CC CA ,
CS CR CC CA are the F1 progeny,
CSCC CSCA CRCC CRCA observed but phenotypically CS is more dominant than CR on the other hand CC is more dominant than CA hence in the offspring two CS (sepia) and two CR russet will be observed. because these two alleles are most dominant than other.
19.
The Bar eye dominant allele BB is dominant over recessive non bar eye bb allele hence the progency having BB and Bb genetotype will be always be having bar eye.
the mm miniature wings allele is dominant over non miniature MM allele hence the progency having mm and mM genotype will always have miniature wings.
the signed britle sn is always dominant over SN allele hence progeny having genotype snsn ans snSN are always signed britle.
female are heterozygous,so that all female are domint for all phenotype hence Bb mM snSN genotype will be observed hence genotype of male will ne autosomal recessive (bb mm SN).
20 LOD score is the loads of the odds. it is used to estimate linkage or genes are closely linked or not. LOD score 3 or >3, the genes are closely linked on same chromosome. some time it is 4. in our case it is 4 (as the graph is marked with line at 4). hence the herbevore resistance gene could be located on chromosome number D (LOD score more than 4)
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