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Which microtubule (MT) population binds to chromosomes during mitosis? (1 point)

ID: 186878 • Letter: W

Question

Which microtubule (MT) population binds to chromosomes during mitosis?

(1 point)

Interpolar MTs

Kinetochore MTs

Astral MTs

Either MT population is able to bind chromosomes because they are functionally redundant

MTs do not associate with chromosomes at all

2.

When does the centrosome duplicate?

(1 point)

In parallel to chromosome segregation in mitosis

In parallel with DNA replication in S-phase

In G1

In G2

In an unregulated manner

3.

Which of the following intermediates of intermediate filament assembly is polar?

(1 point)

Dimer

Tetramer

Octamer

Intermediate filament bundle

None, intermediate filaments are always apolar

4.

Which of the following signals induces the disassembly of the nuclear lamina?

(1 point)

Phosphorylation by a mitotic kinase

Activation of a small GTPase

Fragmentation of the nuclear envelope

A conformational change in lamin A

DNA condensation

Explanation / Answer

1.

Disc-shaped protein structure found at centromere of a chromatid to which microtubules attach during cell division.

2.

Chromosome segregation is a process in which formation of two sister chromatids as a result of DNA replication. The segregation process will occur in both mitosis and meiosis.

3.

Intermediate filaments are non-polar. Intermediate filaments are structural proteins which provide support to cells and tissues.

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