How do you link together multiple amino acids? I’m struggling with how to figure

Question

How do you link together multiple amino acids?
I’m struggling with how to figure out which amino acid goes on the n-terminus and which goes to the c-terminus. My professor stated an example with Methionine, Proline, and Cysteine. She said methionine would be on the n-term and cysteine would be on the c-term while proline would be in the middle. I’m just not understanding how this would be possible. Thank you!! How do you link together multiple amino acids?
I’m struggling with how to figure out which amino acid goes on the n-terminus and which goes to the c-terminus. My professor stated an example with Methionine, Proline, and Cysteine. She said methionine would be on the n-term and cysteine would be on the c-term while proline would be in the middle. I’m just not understanding how this would be possible. Thank you!!
I’m struggling with how to figure out which amino acid goes on the n-terminus and which goes to the c-terminus. My professor stated an example with Methionine, Proline, and Cysteine. She said methionine would be on the n-term and cysteine would be on the c-term while proline would be in the middle. I’m just not understanding how this would be possible. Thank you!!

Explanation / Answer

Methionine is usually present at the N-terminal since AUG is the start codon which also codes for methionine. Most proteins retain this amino acid at their N-terminal. Apart from that, there is no specific order of preference for aminoacid residues at N or C terminal. However amino acids such as proline act as chain breakers which break the secondary structure of proteins.

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