Alkaptonuria is a metabolic disorder in which the affectd persons produce black

Question

Alkaptonuria is a metabolic disorder in which the affectd persons produce black urine. Alkaptonuria results from an allele (a) that is recessive to the allele for normal metabolism (A). Sally has normal metabolism, but her brother has alkaptonuria. Sally’s father has alkaptonuria, and her mother has normal metabolism.


(c) What is the probability that the next three offspring of Sally’s parents will not have alkaptonuria?

(d) Of the next three offspring, any two will be not have alkaptonuria and one will have alkaptonuria?

Explanation / Answer

Father: aa Mother: Aa c) 1/2 x 1/2 x 1/2 =1/8 chance or 12.5% d) 1/2 x 1/2 x 1/2 =1/8 same as above^

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