B) Silent C) Frameshift D) Mis-sense E) All of the above 31. Study the nucleotid

Question

B) Silent C) Frameshift D) Mis-sense E) All of the above 31. Study the nucleotide sequences of wild type and it's mutant gene bel ow. Wild type: Protein: DNA Met - Pro-Glu- Pro- Lys- Met ATG CCC GAA CCCAAAATG Mutant: Protein Met -Pro-Gly- Thr- Gln- Lys DNA ATG CC GGA ACC CAA AAT. This mutation can best be called: A) Non-sense B) Silent C) Frameshift D) Mis-sense E) All of the above The following are examples of large-scale DNA changes in an organism EXCEPT: A) Transformation B) Transduction C) Point mutation 32· D) Conjugation E) Recombination 33 The following describes process of transformation of bacterial cells by DNA: A) Incorporation of naked DNA into a cell. B) Incorporation of DNA into a cell when associated with protein. C) Transfer of DNA from one cell to another cell D) Rearrangement of cellular DNA. 34. A human "B" cellis capable of producing about 15 million IgG proteins by using: A) Recombination process B) alternative splicing process. C) changing the composition of transcription factors D) inducing point mutation. E) Inserting transposons.

Explanation / Answer

31. c) frameshift mutation

A frameshift mutation is a genetic mutation which is caused by insertions or deletions of a number of nucleotides in a DNA sequence not dividable by three.

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