Genetics question. 2. (14 points) Two alleles (Adh and Adh)of the Alcohol Dehydr

Question

Genetics question. 2. (14 points) Two alleles (Adh and Adh)of the Alcohol Dehydrogenase (ADH) gene exist in a large randomly-mating population of Drosophila. Researchers have determined the genotypes of the flies using gel electrophoresis. The number of individuals exhibiting all of the possible genotypes are listed in the table below. What are the allele and genotype frequencies for this population with respect to the Adh locus (please round to 3 decimal places)? Genotype of Flies Adh Adh 45 Adh Adh 210 Adh Adh 245 Total 500 f(AdhFAdhF) 3 o f(Adhs allele 70 f(Adh allele) Suppose that this population of Drosophila gets manipulated such that all matings happen only between individuals that are siblings (F .25). Calculate the expected genotype and allele frequencies in this population after one round of inbreeding. S 43 f(Adhf allele) 30 f(Adhs allele)

Explanation / Answer

2b) Mating between siblings:

Allele frequency of f' Adhf = 0.25

Then, frequency of genotype f' (Adhf Adhf) = (0.25) (0.25) = 0.0625

Frequency of allele f' Adhs = 1 - 0.25 = 0.75

Frequency of genotype f' (Adhf Adhs) = 2 (0.25) (0.75) = 0.375

Frequency of genotype f' (Adhs Adhs ) = (0.75) (0.75) = 0.5625

According to Hardy - Weinberg equation: p2 + 2pq + q2 =1

Now, 0.0625 + 0.375 + 0.5625 = 1

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